Peptide-catalyzed kinetic resolution of planar-chiral metallocenes.
نویسندگان
چکیده
Kinetic resolution of racemic planar-chiral metallocenes was performed through the conjugate addition of a nucleophile to the enal part of substrates. While no enantiomeric discrimination was found with low-molecular-weight organocatalysts, a properly designed resin-supported peptide catalyzed the reaction in a highly selective manner.
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عنوان ژورنال:
- Chemical communications
دوره 50 58 شماره
صفحات -
تاریخ انتشار 2014